MFGE8 anticorps

N° du produit ABIN1449192

Cet anticorps anti-MFGE8 Monoclonal Hamster (Clone 2422) (ABIN1449192) détecte spécifiquement MFGE8 dans IP et FACS. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour MFGE8 anticorps (ABIN1449192)

Antigène: MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp MFGE8 est non-conjugé

Application: Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone: 2422

Détail du produit anti-MFGE8 anticorps

Specificité: This antibody reacts with MFG-E8 short and long form.

Réactivité croisée (Details): Species reactivity (tested):Mouse

Purification: Protein A agarose

Immunogène: Thioglycollate-elicited mouse peritoneal macrophages

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur MFGE8

Antigène: MFGE8 (Milk Fat Globule-EGF Factor 8 Protein (MFGE8))

Autre désignation: Lactadherin

Sujet: Apoptotic cells are rapidly removed by phagocytosis to clear the living cells and tissues of intracellular materials being released from dying cells. Phagocytes recognize apoptotic cells through milk fat globule-EGF-factor 8 (MFG-E8). MFG-E8 is a secreted glycoprotein from thioglycollate-elicited macrophages and bind to phosphatidylserine exposed on the cell surface of apoptotic cells, then bind strongly to cells expressing ανβ3 integrin via its RGD (arginine-glycine-aspartate) motif. Thus, MFG-E8 is an important protein to mediate the engulfment of apoptotic cells by activated macrophages.Synonyms: Breast epithelial antigen BA46, HMFG, MFGE8, MFGM, Milk fat globule-EGF factor 8

ID gène: 4240

NCBI Accession: NP_001108086

UniProt: Q08431

Pathways: SARS-CoV-2 Protein Interactome