PDCD1LG2 anticorps (Extracellular Domain)

N° du produit ABIN1449245

Détail du produit anti-PDCD1LG2 anticorps

Antigène: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Épitope: Extracellular Domain

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp PDCD1LG2 est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: This antibody reacts with mouse CD273 antigen

Purification: Protein A agarose

Immunogène: Recombinant mouse PD-L2 extracellular domain

Clone: 54-1

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur PDCD1LG2

Antigène: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Autre désignation: CD273 / PDL2 (PDCD1LG2 Produits)

Synonymes: anticorps PDL2, anticorps B7DC, anticorps Btdc, anticorps CD273, anticorps PD-L2, anticorps PDCD1L2, anticorps bA574F11.2, anticorps B7-DC, anticorps F730015O22Rik, anticorps programmed cell death 1 ligand 2, anticorps PDCD1LG2, anticorps Pdcd1lg2

Sujet: Programmed death ligand 2 (PD-L2, also known as CD273/B7-DC), a member of B7 family was identified among a library of genes differentially expressed between DCs and activated m acrophages. PD-L2 is a ligand for programmed death 1 (PD-1) which belongs to the CD28/CTLA-4 subfamily. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 + T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. In contrast, at high antigen concentrations, PD-L2-PD-1 interactions reduce cytokine production but do not inhibit T cell proliferation.Synonyms: B7DC, PD-1-ligand 2, PD-L2, PDCD1 ligand 2, PDCD1L2, PDCD1LG2, Programmed cell death 1 ligand 2, Programmed death ligand 2

ID gène: 80380

NCBI Accession: NP_079515

UniProt: Q9BQ51