Integrin beta 3 anticorps

N° du produit ABIN1449278

L’anticorps Rat Monoclonal anti-Integrin beta 3 a été validé pour WB, FACS et IP. Il convient pour détecter Integrin beta 3 dans des échantillons de Souris.

Aperçu rapide pour Integrin beta 3 anticorps (ABIN1449278)

Antigène: Integrin beta 3 (ITGB3)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: 1-55-4

Détail du produit anti-Integrin beta 3 anticorps

Réactivité croisée (Details): Species reactivity (tested):Mouse. Not Human (PBCM cells on Flow cytometry).

Purification: Protein G agarose

Immunogène: Mouse platelet

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur Integrin beta 3

Antigène: Integrin beta 3 (ITGB3)

Autre désignation: CD61 / ITGB3

Sujet: Platelet activation results in a conformational change of the membrane spanning platelet integrin GPIIb/IIIa (aIIbß3, CD41/CD61) enabling the binding of the plasma protein fibrinogen. This binding is primarily reversible, but it enhances platelet activation by outside-in signal causing receptor clustering, platelet secretion, and finally irreversible fibrinogen binding and platelet aggregation.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa

ID gène: 10090

UniProt: O54890

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex