CDKN2B anticorps

N° du produit ABIN1449282

Cet anticorps anti-CDKN2B est un anticorps Souris Monoclonal détectant CDKN2B dans WB, IF et IP. Adapté pour Humain.

Aperçu rapide pour CDKN2B anticorps (ABIN1449282)

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDKN2B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 1F6

Détail du produit anti-CDKN2B anticorps

Specificité: This antibody reacts with p15INK4b (15 kDa).

Réactivité croisée (Details): Species reactivity (tested):Human (HeLa, 293T, transfectant), does not react with Mouse (NIH/3T3, P3U1) and Rat (PC12, Rat1)

Purification: Protein A agarose

Immunogène: GST-full length human p15INK4b

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur CDKN2B

Antigène: CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))

Autre désignation: CDKN2B / p15INK4b

Sujet: Progression through the G1 phase of the cell cycle is regulated in part by the D-type cyclin-dependent kinases, cdk4 and cdk6. p15INK4b is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. Induction of p15INK4b is important for TGFß-mediated cytostasis in epithelial cells but not in hematopoietic cells, it may act as an effector of TGF-ß mediated cell arrest.Synonyms: Cyclin-dependent kinase 4 inhibitor B, MTS2, Multiple tumor suppressor 2, p14-INK4b, p14INK4b, p15-INK4b

ID gène: 1030

NCBI Accession: NP_004927

UniProt: P42772

Pathways: Cycle Cellulaire, Mitotic G1-G1/S Phases