CDCA8 anticorps (N-Term)

N° du produit ABIN1449290

Détail du produit anti-CDCA8 anticorps

Antigène: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Épitope: AA 1-280, N-Term

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDCA8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Specificité: This antibody reacts with Borealin (35 kDa).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A agarose

Immunogène: Recombinant full-length human Borealin (1-280 aa)

Clone: 1D11

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur CDCA8

Antigène: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Autre désignation: CDCA8 / Borealin (CDCA8 Produits)

Synonymes: anticorps BOR, anticorps BOREALIN, anticorps DasraB, anticorps MESRGP, anticorps Bor, anticorps Borr, anticorps CG4454, anticorps Dmel\\CG4454, anticorps dBor, anticorps borea, anticorps Dasra-B, anticorps GgDasraB, anticorps 4831429J16Rik, anticorps AU044747, anticorps Borealin, anticorps D4Ertd421e, anticorps bor, anticorps dasrab, anticorps borealin, anticorps cdca8l, anticorps sb:cb373, anticorps zgc:101607, anticorps cell division cycle associated 8, anticorps borealin-related, anticorps Borealin, anticorps cell division cycle associated 8 L homeolog, anticorps CDCA8, anticorps borr, anticorps borea, anticorps Cdca8, anticorps cdca8.L, anticorps cdca8

Sujet: Borealin is a subunit of the chromosomal passenger complex (CPC), which is necessary for chromosome segregation and cytokinesis. While CPC shows a dynamic localization pattern during mitosis, Borealin and survivin, another subunit of CPC is essential to localize CPC at centromare from prophase to anaphase. It is thought that Borealin and survivin recruit aurora B, a kinase subunit of CPC, to inner centromare to allow phosphorylating appropriate substrates.Synonyms: Cell division cycle-associated protein 8, Dasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein, hDasra-B

ID gène: 55143

NCBI Accession: NP_060571

UniProt: Q53HL2

Pathways: Cycle Cellulaire, M Phase