CDCA8 anticorps (N-Term)

N° du produit ABIN1449290

L’anticorps anti-CDCA8 Monoclonal Souris est utilisé pour la détection de CDCA8 dans des échantillons de Humain. Il a été validé pour WB, IF et IP.

Aperçu rapide pour CDCA8 anticorps (N-Term) (ABIN1449290)

Antigène: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CDCA8 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 1D11

Détail du produit anti-CDCA8 anticorps

Épitope: AA 1-280, N-Term

Specificité: This antibody reacts with Borealin (35 kDa).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A agarose

Immunogène: Recombinant full-length human Borealin (1-280 aa)

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Upon receipt, store (in aliqouts) at -20 °C.

Détails sur CDCA8

Antigène: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Autre désignation: CDCA8 / Borealin

Sujet: Borealin is a subunit of the chromosomal passenger complex (CPC), which is necessary for chromosome segregation and cytokinesis. While CPC shows a dynamic localization pattern during mitosis, Borealin and survivin, another subunit of CPC is essential to localize CPC at centromare from prophase to anaphase. It is thought that Borealin and survivin recruit aurora B, a kinase subunit of CPC, to inner centromare to allow phosphorylating appropriate substrates.Synonyms: Cell division cycle-associated protein 8, Dasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein, hDasra-B

ID gène: 55143

NCBI Accession: NP_060571

UniProt: Q53HL2

Pathways: Cycle Cellulaire, M Phase