DBN1 anticorps (N-Term)

N° du produit ABIN1449383

L’anticorps Souris Monoclonal anti-DBN1 a été validé pour WB et FACS. Il convient pour détecter DBN1 dans des échantillons de Humain.

Aperçu rapide pour DBN1 anticorps (N-Term) (ABIN1449383)

Antigène: DBN1 (Drebrin 1 (DBN1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DBN1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: DBN-N-03

Détail du produit anti-DBN1 anticorps

Épitope: AA 1-326, N-Term

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogène: Bacterially expressed N-terminal fragment of recombinant human drebrin (aa 1-326)

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Tris buffered saline (TBS), pH ~8.0, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DBN1

Antigène: DBN1 (Drebrin 1 (DBN1))

Autre désignation: Drebrin

Sujet: Drebrin is an actin-binding protein, which is expressed mainly in neurons and plays important role in their morphogenesis. The highest level of its expression is in developing brain. Both in neurons and non-neuronal cells drebrin acts as a key regulator of actin cytoskeleton remodelling, affecting especially intercellular junctions, such as dendritic spines of neurons or the immune synapses of T cells. Decrease of drebrin amount in the brain seems to be associated with Alzheimer's disease and Down syndrome, and in case of B-cell precursor acute lymphoblastic leukemia (BCP-ALL) lower drebrin expression correlates with higher risk of relapse.Synonyms: D0S117E, DBN-1, DBN1, DKFZp434D064, Developmentally-regulated brain protein, drebrin 1

ID gène: 1627

NCBI Accession: NP_004386

UniProt: Q16643

Pathways: Maintenance of Protein Location