TFG anticorps
Aperçu rapide pour TFG anticorps (ABIN1449384)
Antigène
Voir toutes TFG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity Chromatography on Protein A
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Immunogène
- Human recombinant protein Trx-his-NTFG.
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Isotype
- IgG2b
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Azide Free PBS, pH ~7.4 preserved by filter sterilization
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Agent conservateur
- Azide free
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TFG (Trk-Fused Gene (TFG))
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Autre désignation
- TFG
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Sujet
- TFG (TRK-fused gene protein) is a regulatory protein with not fully understood function. Its defects are associated with various carcinomas, such as e.g. melanoma, thyroid papillary carcinoma, or glioma. TFG structure (multiple protein interaction motifs) indicated it can be an adaptor protein. It has been demonstrated TFG interacts with proteins modulating the NFkappaB pathway (TANK and NEMO). TNG enhances the effect of TNFalpha, TANK, TRAF2 and TRAF6 in inducing NFkappaB activity.Synonyms: TRK-fused gene protein
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ID gène
- 10342
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NCBI Accession
- NP_001007566
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UniProt
- Q92734
Antigène
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