MEMO1 anticorps (N-Term)

N° du produit ABIN1449397

Cet anticorps Souris Monoclonal détecte spécifiquement MEMO1 dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour MEMO1 anticorps (N-Term) (ABIN1449397)

Antigène: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MEMO1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT1E9

Détail du produit anti-MEMO1 anticorps

Épitope: AA 1-297, N-Term

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein-G affinity chromatography

Immunogène: Recombinant human MEMO1 (1-297aa) purified from E. coli

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MEMO1

Antigène: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Autre désignation: MEMO1

Sujet: MEMO1 (Mediator of ErbB2-driven cell motility 1) is a 297 amino acid protein. It is thought to relax extracellular chemotactic signals that are targeted at the microtubule cytoskeleton, thereby controlling cell migration. Additionally, MEMO1 is required for breast carcinoma migration, suggesting an important role in tumorigenesis. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activitySynonyms: C21orf19-like protein, C2orf4, CGI-27, HCV NS5A-transactivated protein 7, Hepatitis C virus NS5A-transactivated protein 7, Mediator of ErbB2-driven cell motility 1, NS5ATP7

ID gène: 51072

NCBI Accession: NP_057039

UniProt: Q9Y316