SBDS anticorps (N-Term)

N° du produit ABIN1449399

Cet anticorps anti-SBDS est un anticorps Souris Monoclonal détectant SBDS dans WB et EIA. Adapté pour Humain.

Aperçu rapide pour SBDS anticorps (N-Term) (ABIN1449399)

Antigène: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SBDS est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT1E8

Détail du produit anti-SBDS anticorps

Épitope: AA 1-250, N-Term

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein-G affinity chromatography

Immunogène: Recombinant human SBDS (1-250aa) purified from E. coli

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate -Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SBDS

Antigène: SBDS (Shwachman-Bodian-Diamond Syndrome (SBDS))

Autre désignation: SBDS

Sujet: The Shwachman-Bodian-Diamond syndrome (SBDS) is 249 amino acid ribosome maturation protein. The precise function of the SBDS protein is not known but it appears to play an important role in actin cytoskeletal function and mitotic spindle stabilization. Also, SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Mutations in the SBDS gene cause Shwachman-Diamond syndrome (SDS). SDS is an autosomal recessive disorder with clinical features that include pancreatic exocrine insufficiency, haematological dysfunction and skeletal abnormalities.Synonyms: Ribosome maturation protein SBDS, Shwachman-Bodian-Diamond syndrome protein

ID gène: 51119

NCBI Accession: NP_057122

UniProt: Q9Y3A5

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly