PFKM anticorps (N-Term)

N° du produit ABIN1449415

Cet anticorps Souris Monoclonal détecte spécifiquement PFKM dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour PFKM anticorps (N-Term) (ABIN1449415)

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PFKM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT2F11

Détail du produit anti-PFKM anticorps

Épitope: AA 1-780, N-Term

Purification: Protein-A affinity chromatography

Immunogène: Recombinant Human PFKM (1-780aa) purified from E. coli

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate -Buffered Saline ( pH 7.4), 0.02 % Sodium Azide, 10 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PFKM

Antigène: PFKM (phosphofructokinase, Muscle (PFKM))

Autre désignation: PFKM

Sujet: PFKM (phosphofructokinase, muscle) is a regulatory glycolytic enzyme that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease.Synonyms: 6-phosphofructokinase muscle type, GSD7, PFK-1, PFK-A, PFK1, PFKX, Phosphofructo-1-kinase isozyme A, Phosphofructokinase 1, Phosphofructokinase-M, Phosphohexokinase

ID gène: 5213

NCBI Accession: NP_000280

UniProt: P08237

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, L'effet Warburg