ATG5 anticorps (N-Term)

N° du produit ABIN1449605

L’anticorps Lapin Polyclonal anti-ATG5 a été validé pour WB, IF, IHC (p) et EIA. Il convient pour détecter ATG5 dans des échantillons de Humain et Souris.

Aperçu rapide pour ATG5 anticorps (N-Term) (ABIN1449605)

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATG5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-ATG5 anticorps

Épitope: AA 1-30, N-Term

Specificité: This antibody recognizes Human and Mouse ATG5 (N-term). Other species not tested.

Purification: Saturated Ammonium Sulfate precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide between 1~30 amino acids from the N-term of Human APG5L Genename: ATG5

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ATG5

Antigène: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Autre désignation: APG5L / ATG5

Sujet: Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG5, required for autophagy, conjugates to ATG12 and associates with an isolation membrane to form a cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. APG5 may also play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.Synonyms: APG5-like, ASP, Apoptosis-specific protein, Autophagy protein 5

Poids moléculaire: 32447 Da

ID gène: 9474

NCBI Accession: NP_004840

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy