AOC2 anticorps (Middle Region)

N° du produit ABIN1449831

Cet anticorps anti-AOC2 est un anticorps Lapin Polyclonal détectant AOC2 dans WB. Adapté pour Humain, Souris, Boeuf (Vache), Chien, Rat, Poisson zèbre (Danio rerio), Poulet et Xenopus laevis.

Aperçu rapide pour AOC2 anticorps (Middle Region) (ABIN1449831)

Antigène: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Rat, Poisson zèbre (Danio rerio), Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AOC2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-AOC2 anticorps

Épitope: Middle Region

Séquence: AEDIPNTVTL GNRVGFLLRP YNFFDEDPSI FSPGSVYFEK GQDAGLCSIN

Réactivité croisée (Details): Species reactivity (expected):Mouse, Bovine, Rabbit, Dog, PigSpecies reactivity (tested):Human.

Purification: Purified using peptide immunoaffinity column

Immunogène: Synthetic peptide directed towards the middle region of human AOC2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C for one month or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Détails sur AOC2

Antigène: AOC2 (Amine Oxidase, Copper Containing 2 (Retina-Specific) (AOC2))

Autre désignation: AOC2 / RAO

Sujet: Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants.Synonyms: Amine oxidase copper-containing, Retina-specific copper amine oxidase

ID gène: 314

NCBI Accession: NP_033720