ZNF521 anticorps (N-Term)

N° du produit ABIN1449926

L’anticorps anti-ZNF521 Polyclonal Lapin est utilisé pour la détection de ZNF521 dans des échantillons de Humain. Il a été validé pour WB, IF et EIA.

Aperçu rapide pour ZNF521 anticorps (N-Term) (ABIN1449926)

Antigène: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF521 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-ZNF521 anticorps

Épitope: N-Term

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid synthetic peptide near the amino terminus of Human ZNF521

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ZNF521

Antigène: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Autre désignation: ZNF521

Sujet: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors . ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis .Synonyms: EHZF, Early hematopoietic zinc finger protein, LIP3, LYST-interacting protein 3, Zinc finger protein 521

ID gène: 25925

NCBI Accession: NP_056276