ZNF521 anticorps (C-Term)

N° du produit ABIN6991449

Détail du produit anti-ZNF521 anticorps

Antigène: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Épitope: AA 1160-1210, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNF521 est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: ZNF521 antibody is human specific.

Purification: ZNF521 Antibody is affinity chromatography purified via peptide column.

Immunogène: ZNF521 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ZNF521. The immunogen is located within amino acids 1160 - 1210 of ZNF521.

Isotype: IgG

Information d'application

Indications d'application: ZNF521 antibody can be used for detection of ZNF521 by immunohistochemistry at 5 μ,g/mL.

Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZNF521 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ZNF521 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur ZNF521

Antigène: ZNF521 (Zinc Finger Protein 521 (ZNF521))

Autre désignation: ZNF521 (ZNF521 Produits)

Synonymes: anticorps Znf521, anticorps EHZF, anticorps Evi3, anticorps B930086A16Rik, anticorps zinc finger protein 521, anticorps zinc finger protein 521 S homeolog, anticorps Zfp521, anticorps ZNF521, anticorps znf521.S

Sujet: ZNF521 Antibody: The zinc finger protein 521 (ZNF521) is a transcription factor containing an N-terminal transcriptional repressor motif and 30 zinc finger domains. It plays a role in both erythroid cell and osteoblast differentiation during development, inhibiting the activities of early B-cell factor 1 (EBF1) in erythroid cells and Runx2 in osteoblast precursors. ZFP521 binds to both Runx2 and histone deacetylase 3 (HDAC3), promotes their association and antagonizes Runx2 transcriptional activity in a HDAC3-dependent manner, thereby regulating osteoblast differentiation, skeletal development, and bone homeostasis.

ID gène: 25925

NCBI Accession: NP_056276

UniProt: Q96K83