Centriolin anticorps (C-Term)

N° du produit ABIN1449934

Détail du produit anti-Centriolin anticorps

Antigène: Centriolin (CNTRL)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Centriolin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 17 amino acid synthetic peptide near the carboxy terminus of Human CCP110

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Centriolin

Antigène: Centriolin (CNTRL)

Autre désignation: CEP110 (CNTRL Produits)

Synonymes: anticorps CEP1, anticorps CEP110, anticorps FAN, anticorps bA165P4.1, anticorps Cep1, anticorps Cep110, anticorps 6720467O09Rik, anticorps AA968343, anticorps Cntrl, anticorps IB3/5, anticorps Ma2a8, anticorps b2b1468Clo, anticorps centriolin, anticorps CNTRL, anticorps Cntrl

Sujet: CCP110 is a centrosomal protein required for the centrosome to function as a microtubule organizing center and plays an essential role in centrosome duplication. It is a target of cyclin-dependent kinases (CDKs), disruption of CCP110 phosphorylation leads to unscheduled centrosome separation and polyploidy. CCP110 is also a target of SCF (Cyclin F) ubiquitin ligase complex, leading to its degradation, suggesting that this complex controls centrosome homeostasis and mitotic fidelity through CCP110 degradation. The centriolar kinesin Kif24 also interacts with CP110 and remodel microtubules and regulate ciliogenesis.Synonyms: CP110, Centrosomal protein of 110 kDa, KIAA0419

ID gène: 9738

NCBI Accession: NP_001185951

Pathways: M Phase, SARS-CoV-2 Protein Interactome