KCP anticorps (C-Term)

N° du produit ABIN1449940

Détail du produit anti-KCP anticorps

Antigène: KCP (Kielin/Chordin-Like Protein (KCP))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCP est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: 15 amino acid synthetic peptide near the carboxy terminus of Human CRIM2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KCP

Antigène: KCP (Kielin/Chordin-Like Protein (KCP))

Autre désignation: CRIM2 (KCP Produits)

Synonymes: anticorps CRIM2, anticorps KCP1, anticorps NET67, anticorps AW060220, anticorps CRIM-2, anticorps Crim2, anticorps Gm793, anticorps KCP-1, anticorps RGD1561119, anticorps crim2, anticorps kielin/chordin-like protein, anticorps kielin/chordin-like protein L homeolog, anticorps KCP, anticorps LOC515624, anticorps Kcp, anticorps kcp.L

Sujet: CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-beta1, suppressing activin- and TGF-beta1-dependent transcription.Synonyms: CRIM-2, Cysteine-rich motor neuron 2 protein, KCP1, NET67, kielin/chordin-like protein

ID gène: 375616

NCBI Accession: NP_001129386