KCP anticorps (C-Term)

N° du produit ABIN6991728

Détail du produit anti-KCP anticorps

Antigène: KCP (Kielin/Chordin-Like Protein (KCP))

Épitope: AA 1320-1370, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCP est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: At least two isoforms of CRIM2 are known to exist, this antibody will only detect the larger isoform. CRIM2 antibody is predicted to not cross-react with CRIM1.

Purification: CRIM2 Antibody is affinity chromatography purified via peptide column.

Immunogène: CRIM2 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human CRIM2. The immunogen is located within amino acids 1320 - 1370 of CRIM2.

Isotype: IgG

Information d'application

Indications d'application: CRIM2 antibody can be used for detection of CRIM2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: CRIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: CRIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur KCP

Antigène: KCP (Kielin/Chordin-Like Protein (KCP))

Autre désignation: CRIM2 (KCP Produits)

Synonymes: anticorps CRIM2, anticorps KCP1, anticorps NET67, anticorps AW060220, anticorps CRIM-2, anticorps Crim2, anticorps Gm793, anticorps KCP-1, anticorps RGD1561119, anticorps crim2, anticorps kielin/chordin-like protein, anticorps kielin/chordin-like protein L homeolog, anticorps KCP, anticorps LOC515624, anticorps Kcp, anticorps kcp.L

Sujet: CRIM2 Antibody: CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling. It binds to BMP7, a morphogen that is important for kidney development and part of the kidney's physiological response to repair of acute kidney injury, enhancing its binding to its receptor. Because of this, CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury. CRIM2 can also interact directly with either activin or TGF-β,1, suppressing activin- and TGF-β,1-dependent transcription.

ID gène: 375616

NCBI Accession: NP_001129386

UniProt: Q6ZWJ8