CASK anticorps (N-Term)
Aperçu rapide pour CASK anticorps (N-Term) (ABIN1449948)
Antigène
Voir toutes CASK AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse, Rat.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 16 amino acid synthetic peptide near the amino terminus of Human CASK
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))
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Autre désignation
- CASK
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Sujet
- CASK (Calcium/calmodulin-dependent serine protein kinase), a conserved multi-domain scaffolding protein, belongs to a MAGUK (membrane-associated guanylate kinase homologs) subfamily and is involved in cell junction organization, tumor suppression and signaling. It is characterized by a novel domain structure that consists of a calcium/calmodulin-dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is ubiquitously expressed and significantly greater in brain where it is thought to be involved in signaling at neuronal synapses. CASK interacts with CASKINs and defects in CASK are the cause of mental retardation X-linked CASK-related.Synonyms: Calcium/calmodulin-dependent serine protein kinase, LIN2, Lin-2 homolog, Peripheral plasma membrane protein CASK
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ID gène
- 8573
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NCBI Accession
- NP_003679
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Pathways
- Synaptic Vesicle Exocytosis
Antigène
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