DELE1/KIAA0141 anticorps (N-Term)

N° du produit ABIN1449949

Cet anticorps Lapin Polyclonal détecte spécifiquement DELE1/KIAA0141 dans WB, IF et EIA. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour DELE1/KIAA0141 anticorps (N-Term) (ABIN1449949)

Antigène: DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DELE1/KIAA0141 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-DELE1/KIAA0141 anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid synthetic peptide near the amino terminus of Human DELE

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur DELE1/KIAA0141

Antigène: DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

Autre désignation: KIAA0141

Sujet: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-alpha and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-alpha, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.

ID gène: 9812

NCBI Accession: NP_055588