DELE1/KIAA0141 anticorps (N-Term)
Aperçu rapide pour DELE1/KIAA0141 anticorps (N-Term) (ABIN6991710)
Antigène
Voir toutes DELE1/KIAA0141 (DELE1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Purification
- DELE Antibody is affinity chromatography purified via peptide column.
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Immunogène
- DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE. The immunogen is located within the first 50 amino acids of DELE.
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Isotype
- IgG
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Indications d'application
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DELE antibody can be used for detection of DELE by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- DELE Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- DELE antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))
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Autre désignation
- DELE
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Sujet
- DELE Antibody: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α, and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.
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ID gène
- 9812
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NCBI Accession
- NP_055588
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UniProt
- Q14154
Antigène
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