KPNA7 anticorps (N-Term)

N° du produit ABIN1449957

Détail du produit anti-KPNA7 anticorps

Antigène: KPNA7 (Karyopherin alpha 7 (Importin alpha 8) (KPNA7))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA7 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: 13 amino acid synthetic peptide near the amino terminus of Human KPNA7

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KPNA7

Antigène: KPNA7 (Karyopherin alpha 7 (Importin alpha 8) (KPNA7))

Autre désignation: KPNA7 (KPNA7 Produits)

Synonymes: anticorps KPNA7, anticorps AW146299, anticorps Gm1055, anticorps karyopherin subunit alpha 7, anticorps karyopherin alpha 7 (importin alpha 8), anticorps KPNA7, anticorps kpna7, anticorps Kpna7

Sujet: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.Synonyms: Importin alpha 8, Importin subunit alpha-8, Karyopherin alpha 7, Karyopherin subunit alpha-7

ID gène: 402569

NCBI Accession: NP_001139187

Pathways: Protein targeting to Nucleus