KPNA7 anticorps (N-Term)

N° du produit ABIN6991419

Détail du produit anti-KPNA7 anticorps

Antigène: KPNA7 (Karyopherin alpha 7 (Importin alpha 8) (KPNA7))

Épitope: AA 40-90, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KPNA7 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: KPNA7 antibody is human specific. KPNA7 antibody is predicted to not cross-react with other Importin alpha family members.

Purification: KPNA7 Antibody is affinity chromatography purified via peptide column.

Immunogène: KPNA7 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human KPNA7. The immunogen is located within amino acids 40 - 90 of KPNA7.

Isotype: IgG

Information d'application

Indications d'application: KPNA7 antibody can be used for detection of KPNA7 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: KPNA7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: KPNA7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur KPNA7

Antigène: KPNA7 (Karyopherin alpha 7 (Importin alpha 8) (KPNA7))

Autre désignation: KPNA7 (KPNA7 Produits)

Synonymes: anticorps KPNA7, anticorps AW146299, anticorps Gm1055, anticorps karyopherin subunit alpha 7, anticorps karyopherin alpha 7 (importin alpha 8), anticorps KPNA7, anticorps kpna7, anticorps Kpna7

Sujet: KPNA7 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA7 is most closely related to KPNA2, but unlike KPNA2, KPNA7 primarily localizes to the nucleus. It has been suggested that KPNA7 may play a role in the transport of essential nuclear proteins required for early embryogenesis.

ID gène: 402569

NCBI Accession: NP_001139187

UniProt: A9QM74

Pathways: Protein targeting to Nucleus