WDR35 anticorps (N-Term)

N° du produit ABIN1449959

Détail du produit anti-WDR35 anticorps

Antigène: WDR35 (WD Repeat Domain 35 (WDR35))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDR35 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid synthetic peptide near the amino terminus of Human WDR35

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur WDR35

Antigène: WDR35 (WD Repeat Domain 35 (WDR35))

Autre désignation: WDR35 (WDR35 Produits)

Synonymes: anticorps 4930459M12Rik, anticorps 4931430C06, anticorps mKIAA1336, anticorps RGD1564116, anticorps Wdr35, anticorps CED2, anticorps IFT121, anticorps im:7159945, anticorps si:ch211-206k20.4, anticorps WD repeat domain 35, anticorps Wdr35, anticorps WDR35, anticorps wdr35

Sujet: WD40 repeats are a common structural module in eukaryotic proteins, and proteins containing WD40 domains have a wide range of functions, including signal transduction, cell cycle regulation, RNA splicing, and transcription. One such protein, WDR35, also known as CED2, has been shown to be mutated in patients with Sensenbrenner syndrome/cranioectodermal dysplasia (CED), an autosomal-recessive disease that is characterized by craniosynstosis and ectodermal and skeletal abnormalities. WDR35 localizes to cilia and dentrosomes during embryogenesis and human and mouse fibroblasts that lack this gene fail to produce cilia. Mutations in this gene can also cause short-rib polydactyly syndromes due to abnormal ciliogenesis.Synonyms: IFT121, Intraflagellar transport protein 121 homolog, KIAA1336, WD repeat-containing protein 35

ID gène: 57539

NCBI Accession: NP_001006658

Pathways: Signalisation Hedgehog