BATF anticorps (N-Term)

N° du produit ABIN1449967

Cet anticorps Lapin Polyclonal détecte spécifiquement BATF dans WB, IF et EIA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour BATF anticorps (N-Term) (ABIN1449967)

Antigène: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BATF est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Détail du produit anti-BATF anticorps

Épitope: N-Term

Purification: Affinity chromatography purified via peptide column

Immunogène: 16 amino acid synthetic peptide near the amino terminus of Human BATF

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BATF

Antigène: BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))

Autre désignation: BATF

Sujet: BATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events and blocks cellular transformation by Ras and Fos. BATF also is required for the differentiation of IL-17-producing T helper (TH17) cells, a CD4+ subset of T cells that coordinates the inflammatory response in host defense. In both T cells and B cells, BATF is required for the appropriate regulation of the class-switch recombination.Synonyms: B-ATF, B-cell activating transcription factor, Basic leucine zipper transcriptional factor ATF-like, SF-HT-activated gene 2 protein, SFA-2, SFA2

Poids moléculaire: 14 kDa

ID gène: 10538

NCBI Accession: NP_006390