SGSM1 anticorps (Middle Region)
Aperçu rapide pour SGSM1 anticorps (Middle Region) (ABIN1449980)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody (in aliquots) at -20 °C.
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- SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))
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Autre désignation
- SGSM1
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Sujet
- Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.Synonyms: RUTBC2, Small G protein signaling modulator 1
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Poids moléculaire
- 126 kDa
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ID gène
- 129049
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NCBI Accession
- NP_001035037
Antigène
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