SGSM1 anticorps (AA 480-530)
Aperçu rapide pour SGSM1 anticorps (AA 480-530) (ABIN6991753)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 480-530
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Specificité
- At least four isoforms of SGSM1 are known to exist, SGSM1 antibody will detect all four isoforms.
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Purification
- SGSM1 Antibody is affinity chromatography purified via peptide column.
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Immunogène
- SGSM1 antibody was raised against a 17 amino acid synthetic peptide near the center of human SGSM1. The immunogen is located within amino acids 480 - 530 of SGSM1.
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Isotype
- IgG
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Indications d'application
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SGSM1 antibody can be used for detection of SGSM1 by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- SGSM1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,4 °C
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Stockage commentaire
- SGSM1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SGSM1 (Small G Protein Signaling Modulator 1 (SGSM1))
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Autre désignation
- SGSM1
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Sujet
- SGSM1 Antibody: Small G proteins such as RAP and RAB proteins are the key molecules in intracellular signal transduction and vesicle transportation. A novel protein family small G protein signaling modulator (SGSM) consisting of three members SGSM1-3 bind to RAP and RAB family proteins. All three SGSM proteins possess both a RUN domain and a TBC domain. SGSM1 (RUTBC2) is a 1,148 amino acid protein that localizes to the Golgi apparatus and is mainly expressed in the CNS. SGSM1 interacts with RAP and RAB subfamily members of the small G proteins, and function as modulators of RAP and RAB-mediated neuronal signal transduction and vesicular transportation pathways.
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Poids moléculaire
- 126 kDa
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ID gène
- 129049
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NCBI Accession
- NP_001035037
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UniProt
- Q2NKQ1
Antigène
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