CHD7 anticorps (N-Term)
Aperçu rapide pour CHD7 anticorps (N-Term) (ABIN1450043)
Antigène
Voir toutes CHD7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
-
Purification
- Affinity chromatography purified via peptide column
-
Immunogène
- CHD7 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CHD7
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- PBS containing 0.02 % Sodium Azide as preservative
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- CHD7 (Chromodomain Helicase DNA Binding Protein 7 (CHD7))
-
Autre désignation
- CHD7
-
Sujet
- CHD proteins belong to a superfamily of proteins of ATP-dependent chromatin remodeling enzymes that have a unique combination of functional domains, including two N-terminal chromodomains, a SNF2-like ATPase/helicase domain and a DNA-binding domain. These proteins are thought to play a role in early embryonic development by affecting chromatin structure and gene expression. Mutations in one member of this family, CHD7, result in CHARGE syndrome. It colocalizes with embryonic stem (ES) cell master regulators OCT4/POU5F1, SOX2, and NANOG and is thought to modulate ES-specific gene transcription. Together with SOX2, CHD7 has been suggested to also regulate several human disease genes.Synonyms: ATP-dependent helicase CHD7, CHD-7, Chromodomain-helicase-DNA-binding protein 7, KIAA1416
-
ID gène
- 55636
-
UniProt
- Q9P2D1
-
Pathways
- Sensory Perception of Sound, Chromatin Binding
Antigène
-