SEC62 anticorps (C-Term)

N° du produit ABIN1450053

Détail du produit anti-SEC62 anticorps

Antigène: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC62 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid synthetic peptide near the carboxy terminus of Human SEC62

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SEC62

Antigène: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Autre désignation: SEC62 / TLOC1 (TLOC1 Produits)

Synonymes: anticorps tloc1, anticorps TLOC1, anticorps wu:fb57b06, anticorps zgc:114073, anticorps Dtrp1, anticorps HTP1, anticorps TP-1, anticorps 3100002M17Rik, anticorps AI844545, anticorps AW545092, anticorps Tloc1, anticorps Ab2-292, anticorps SEC62 homolog, preprotein translocation factor S homeolog, anticorps SEC62 homolog, preprotein translocation factor, anticorps membrane unit of ER protein translocation apparatus, anticorps SEC62 homolog (S. cerevisiae), anticorps sec62.S, anticorps SEC62, anticorps sec62, anticorps Sec62

Sujet: SEC62 is an integral membrane protein located in the rough endoplasmic reticulum (ER) and is part of the SEC61-SEC62-SEC63 complex that is the central component of the protein translocation apparatus of the ER membrane. It is speculated that SEC61-SEC62-SEC63 may perform post-translational protein translocation into the ER and might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. Silencing of this gene with RNAi dramatically reduced the migration and invasive potential of numerous tumor cell lines, suggesting that it may be an attractive target for therapy of various tumors.Synonyms: Translocation protein 1, Translocation protein SEC62

ID gène: 7095

NCBI Accession: NP_003253