DRAXIN anticorps (C-Term)
Aperçu rapide pour DRAXIN anticorps (C-Term) (ABIN1450058)
Antigène
Voir toutes DRAXIN AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse, Rat.
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Purification
- Affinity chromatography purified via peptide column
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Immunogène
- 17 amino acid synthetic peptide near the carboxy terminus of Human Neucrin
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
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Autre désignation
- Draxin
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Sujet
- Neucrin, also known as Draxin, is a repulsive guidance protein for the spinal cord and forebrain commissures. It is thought to act as an antagonist of canonical Wnt signaling by inhibiting the stabilization of cytosolic beta-catenin. Ectopically expressed neucrin inhibited growth or caused misrouting of chick spinal cord commissural axons in vivo while Neucrin-null mice showed defasciculation of spinal cord commissural axons and an absence of all forebrain commisures. Other experiments in mice have shown that olfactory bulb axonal outgrowth is inhibited by Neucrin, suggesting that Neucrin functions as an inhibitory guidance cue for olfactory bulb axons.Synonyms: C1orf187, Dorsal repulsive axon guidance protein, Neucrin, PSEC0258
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ID gène
- 374946
Antigène
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