TSHZ3 anticorps (N-Term)

N° du produit ABIN1450132

Cet anticorps Lapin Polyclonal détecte spécifiquement TSHZ3 dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TSHZ3 anticorps (N-Term) (ABIN1450132)

Antigène: TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSHZ3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-TSHZ3 anticorps

Épitope: N-Term

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse, Rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 18 amino acid synthetic peptide near the amino terminus of human TSHZ3 / ZNF537

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TSHZ3

Antigène: TSHZ3 (Teashirt Zinc Finger Homeobox 3 (TSHZ3))

Autre désignation: TSHZ3 / ZNF537

Sujet: The Teashirt zinc finger homeobox (TSHZ) family comprise a family of evolutionarily conserved transcription factors that, in Drosophila, are active in specific body parts for patterning, but whose function in vertebrates is less clear. In mice, the known three TSHZ proteins are expressed in distinct patterns in the developing and adult brain, suggesting that they play a role in the establishment of regional identity and specification of cell types within the brain. Both TSHZ3 and TSHZ1 have been found to interact with FE65, an adapter protein that binds to the amyloid protein precursor (APP) in neurons. Together with SET, a component of the inhibitor of acetyl transferase, and histone deacetylases, these proteins formed a gene-silencing complex whose target includes caspase-4. Recent experiments have also suggested this family of proteins may be involved in carcinogenesis.Synonyms: KIAA1474, TSH3, Teashirt homolog 3, Zinc finger protein 537

ID gène: 57616

NCBI Accession: NP_065907

Pathways: Regulation of Muscle Cell Differentiation