HHATL anticorps (N-Term)

N° du produit ABIN1450142

Détail du produit anti-HHATL anticorps

Antigène: HHATL (Hedgehog Acyltransferase-Like (HHATL))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HHATL est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogène: 19 amino acid synthetic peptide near the amino terminus of Human HHATL

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HHATL

Antigène: HHATL (Hedgehog Acyltransferase-Like (HHATL))

Autre désignation: GUP1 / HHATL (HHATL Produits)

Synonymes: anticorps Gup1, anticorps RGD1311911, anticorps gup1, anticorps oact3, anticorps mboat3, anticorps MGC53261, anticorps mstp002, anticorps MGC89797, anticorps GUP1, anticorps 1110011D13Rik, anticorps C3orf3, anticorps MBOAT3, anticorps MSTP002, anticorps OACT3, anticorps c3orf3b, anticorps gup1b, anticorps im:7145545, anticorps wu:fc04e05, anticorps zgc:154131, anticorps c3orf3a, anticorps gup1a, anticorps zgc:77750, anticorps hedgehog acyltransferase-like, anticorps hedgehog acyltransferase like S homeolog, anticorps hedgehog acyltransferase like, anticorps hedgehog acyltransferase like, b, anticorps hedgehog acyltransferase like, a, anticorps Hhatl, anticorps hhatl.S, anticorps HHATL, anticorps hhatl, anticorps hhatlb, anticorps hhatla

Sujet: The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development .Synonyms: C3orf3, Glycerol uptake/transporter homolog, Hedgehog acyltransferase-like protein, KIAA1173, Protein-cysteine N-palmitoyltransferase HHAT-like protein

ID gène: 57467

NCBI Accession: NP_065758

Pathways: Signalisation Hedgehog