MAX anticorps (pSer2)

N° du produit ABIN1450344

Cet anticorps anti-MAX Polyclonal Lapin (ABIN1450344) détecte spécifiquement MAX dans ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MAX anticorps (pSer2) (ABIN1450344)

Antigène: MAX (MYC Associated Factor X (MAX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAX est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-MAX anticorps

Épitope: AA 1-50, pSer2

Fonction: Max (phospho Ser2) Antibody

Specificité: Phospho-Max (S2) Polyclonal Antibody detects endogenous levels of Max protein only when phosphorylated at S2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human MAX around the phosphorylation site of Ser2. AA range:1-50

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MAX

Antigène: MAX (MYC Associated Factor X (MAX))

Autre désignation: MAX

Sujet:

Synonyms: MAX, BHLHD4, Protein max, Class D basic helix-loop-helix protein 4, bHLHd4, Myc-associated factor X

Background: The protein encoded byThis gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],

Gene Name: MAX

Protein Name: Protein max

Poids moléculaire: 18 kDa

ID gène: 4149

OMIM: 154950

UniProt: P61244

Pathways: Mitotic G1-G1/S Phases