PINX1 anticorps (AA 121-170)

N° du produit ABIN1450857

Cet anticorps anti-PINX1 Polyclonal Lapin (ABIN1450857) détecte spécifiquement PINX1 dans ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PINX1 anticorps (AA 121-170) (ABIN1450857)

Antigène: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PINX1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-PINX1 anticorps

Épitope: AA 121-170

Fonction: PinX1 Antibody

Specificité: PinX1 Polyclonal Antibody detects endogenous levels of PinX1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human PINX1. AA range:121-170

Isotype: IgG

Information d'application

Indications d'application: IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur PINX1

Antigène: PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))

Autre désignation: PINX1

Sujet:

Synonyms: PINX1, LPTL, LPTS, PIN2/TERF1-interacting telomerase inhibitor 1, Liver-related putative tumor suppressor, Pin2-interacting protein X1, Protein 67-11-3, TRF1-interacting protein 1

Background: domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity:Contains 1 G-patch domain.,subcellular location:In nucleoli and at telomere speckles.,subunit:Binds to MCRS1, TERT and TERF1.,tissue specificity:Ubiquitous, expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,

Gene Name: PINX1

Protein Name: PIN2/TERF1-interacting telomerase inhibitor 1

Poids moléculaire: 37 kDa

ID gène: 54984

OMIM: 606505

UniProt: Q96BK5