TROVE2 anticorps (AA 311-360)

N° du produit ABIN1450995

Cet anticorps anti-TROVE2 Polyclonal Lapin (ABIN1450995) détecte spécifiquement TROVE2 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TROVE2 anticorps (AA 311-360) (ABIN1450995)

Antigène: TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TROVE2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-TROVE2 anticorps

Épitope: AA 311-360

Fonction: RO60 Antibody

Specificité: RO60 Polyclonal Antibody detects endogenous levels of RO60 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human TROVE2. AA range:311-360

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TROVE2

Antigène: TROVE2 (TROVE Domain Family, Member 2 (TROVE2))

Autre désignation: TROVE2

Sujet:

Synonyms: TROVE2, RO60, SSA2, 60 kDa SS-A/Ro ribonucleoprotein, 60 kDa Ro protein, 60 kDa ribonucleoprotein Ro, RoRNP, Ro 60 kDa autoantigen, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, SS-A, TROVE domain family member 2

Background: disease:Sera from patients with systemic lupus erythematosus (SLE) often contain antibodies that react with the normal cellular SSA2 protein as if this antigen was foreign.,function:RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the Ro 60 kDa family.,similarity:Contains 1 TROVE domain.,subunit:Found in a complex with PUF60 and Y5 RNA. Interacts with RIP11.,

Gene Name: TROVE2

Protein Name: 60 kDa SS-A/Ro ribonucleoprotein

Poids moléculaire: 60 kDa

ID gène: 6738

OMIM: 600063

UniProt: P10155