Manic Fringe anticorps (AA 61-110)

N° du produit ABIN1451061

Cet anticorps anti-Manic Fringe Polyclonal Lapin (ABIN1451061) détecte spécifiquement Manic Fringe dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Manic Fringe anticorps (AA 61-110) (ABIN1451061)

Antigène: Manic Fringe (MFNG) (MFNG)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Manic Fringe est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Manic Fringe anticorps

Épitope: AA 61-110

Fonction: Manic Fringe Antibody

Specificité: Manic Fringe Polyclonal Antibody detects endogenous levels of Manic Fringe protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human MFNG. AA range:61-110

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Manic Fringe

Antigène: Manic Fringe (MFNG) (MFNG)

Autre désignation: MFNG

Sujet:

Synonyms: MFNG, Beta-1, 3-N-acetylglucosaminyltransferase manic fringe, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Background: This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. [provided by RefSeq, Oct 2009],

Gene Name: MFNG

Protein Name: Beta-1,3-N-acetylglucosaminyltransferase manic fringe

Poids moléculaire: 36 kDa

ID gène: 4242

OMIM: 602577

UniProt: O00587

Pathways: Signalisation Notch