RNF111 anticorps (AA 901-950)

N° du produit ABIN1451235

Cet anticorps anti-RNF111 Polyclonal Lapin (ABIN1451235) détecte spécifiquement RNF111 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour RNF111 anticorps (AA 901-950) (ABIN1451235)

Antigène: RNF111 (Ring Finger Protein 111 (RNF111))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF111 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-RNF111 anticorps

Épitope: AA 901-950

Fonction: Arkadia Antibody

Specificité: Arkadia Polyclonal Antibody detects endogenous levels of Arkadia protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human RNF111. AA range:901-950

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur RNF111

Antigène: RNF111 (Ring Finger Protein 111 (RNF111))

Autre désignation: RNF111

Sujet:

Synonyms: RNF111, E3 ubiquitin-protein ligase Arkadia, RING finger protein 111

Background: ring finger protein 111(RNF111) Homo sapiens The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],

Gene Name: RNF111

Protein Name: E3 ubiquitin-protein ligase Arkadia

Poids moléculaire: 108 kDa

ID gène: 54778

OMIM: 605840

UniProt: Q6ZNA4