MASP2 anticorps (AA 227-276)

N° du produit ABIN1451319

Cet anticorps anti-MASP2 Polyclonal Lapin (ABIN1451319) détecte spécifiquement MASP2 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MASP2 anticorps (AA 227-276) (ABIN1451319)

Antigène: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MASP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MASP2 anticorps

Épitope: AA 227-276

Fonction: MASP-2 Antibody

Specificité: MASP-2 Polyclonal Antibody detects endogenous levels of MASP-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human MASP2. AA range:227-276

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MASP2

Antigène: MASP2 (Mannan-Binding Lectin serine Peptidase 2 (MASP2))

Autre désignation: MASP2

Sujet:

Synonyms: MASP2, Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2

Background: mannan binding lectin serine peptidase 2(MASP2) Homo sapiens This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],

Gene Name: MASP2

Protein Name: Mannan-binding lectin serine protease 2

Poids moléculaire: 75 kDa

ID gène: 10747

OMIM: 605102

UniProt: O00187

Pathways: Système du Complément