RGS14 anticorps (AA 125-174)

N° du produit ABIN1451538

Cet anticorps anti-RGS14 Polyclonal Lapin (ABIN1451538) détecte spécifiquement RGS14 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour RGS14 anticorps (AA 125-174) (ABIN1451538)

Antigène: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RGS14 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RGS14 anticorps

Épitope: AA 125-174

Fonction: RGS14 Antibody

Specificité: RGS14 Polyclonal Antibody detects endogenous levels of RGS14 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human RGS14. AA range:125-174

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300, ELISA 2000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur RGS14

Antigène: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Autre désignation: RGS14

Sujet:

Synonyms: RGS14, Regulator of G-protein signaling 14, RGS14

Background: This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],

Gene Name: RGS14

Protein Name: Regulator of G-protein signaling 14

Poids moléculaire: 64 kDa

ID gène: 10636

OMIM: 602513

UniProt: O43566

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling