NKX2-8 anticorps (AA 20-69)

N° du produit ABIN1451871

Cet anticorps anti-NKX2-8 Polyclonal Lapin (ABIN1451871) détecte spécifiquement NKX2-8 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NKX2-8 anticorps (AA 20-69) (ABIN1451871)

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NKX2-8 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NKX2-8 anticorps

Épitope: AA 20-69

Fonction: Nkx-2.8 Antibody

Specificité: Nkx-2.8 Polyclonal Antibody detects endogenous levels of Nkx-2.8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human NKX28. AA range:20-69

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur NKX2-8

Antigène: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Autre désignation: NKX28

Sujet:

Background: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. [provided by RefSeq, Dec 2015],

Gene Name: NKX2-8

Protein Name: Homeobox protein Nkx-2.8

Poids moléculaire: 25 kDa

ID gène: 26257

OMIM: 603245

UniProt: Q8IUT7