CA9 anticorps (AA 33-82)
Aperçu rapide pour CA9 anticorps (AA 33-82) (ABIN1452999)
Antigène
Voir toutes CA9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 33-82
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Fonction
- CA IX Antibody
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Specificité
- CA IX Polyclonal Antibody detects endogenous levels of CA IX protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from human CA IX. AA range:33-82
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- CA9 (Carbonic Anhydrase IX (CA9))
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Autre désignation
- CA IX
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Sujet
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Synonyms: CA9, G250, MN, Carbonic anhydrase 9, Carbonate dehydratase IX, Carbonic anhydrase IX, CA-IX, CAIX, Membrane antigen MN, P54/58N, Renal cell carcinoma-associated antigen G250, RCC-associated antigen G250, pMW1
Background: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014],
Gene Name: CA9
Protein Name: Carbonic anhydrase 9
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Poids moléculaire
- 49 kDa
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ID gène
- 768
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OMIM
- 603179
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UniProt
- Q16790
Antigène
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