DDR1 anticorps (AA 749-798)

N° du produit ABIN1453188

Cet anticorps anti-DDR1 Polyclonal Lapin (ABIN1453188) détecte spécifiquement DDR1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour DDR1 anticorps (AA 749-798) (ABIN1453188)

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DDR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-DDR1 anticorps

Épitope: AA 749-798

Fonction: DDR1 Antibody

Specificité: DDR1 Polyclonal Antibody detects endogenous levels of DDR1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human DDR1. AA range:749-798

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur DDR1

Antigène: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Autre désignation: DDR1

Sujet:

Synonyms: DDR1, CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE, Epithelial discoidin domain-containing receptor 1, Epithelial discoidin domain receptor 1, CD167 antigen-like family member A, Cell adhesion kinase, Discoidin receptor tyrosine kinase, HGK2,

Background: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism.The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011],

Gene Name: DDR1

Protein Name: Epithelial discoidin domain-containing receptor 1

Poids moléculaire: 101 kDa

ID gène: 780

OMIM: 600408

UniProt: Q08345

Pathways: Signalisation RTK, Smooth Muscle Cell Migration