BIRC7 anticorps (AA 162-211)

N° du produit ABIN1453581

Cet anticorps anti-BIRC7 Polyclonal Lapin (ABIN1453581) détecte spécifiquement BIRC7 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour BIRC7 anticorps (AA 162-211) (ABIN1453581)

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BIRC7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-BIRC7 anticorps

Épitope: AA 162-211

Fonction: ML-IAP Antibody

Specificité: ML-IAP Polyclonal Antibody detects endogenous levels of ML-IAP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human ML-IAP. AA range:162-211

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur BIRC7

Antigène: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Autre désignation: ML-IAP

Sujet:

Synonyms: BIRC7, KIAP, LIVIN, MLIAP, RNF50, Baculoviral IAP repeat-containing protein 7, Kidney inhibitor of apoptosis protein, KIAP, Livin, Melanoma inhibitor of apoptosis protein, ML-IAP, RING finger protein 50

Background: This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants [provided by RefSeq, Jul 2013],

Gene Name: BIRC7

Protein Name: Baculoviral IAP repeat-containing protein 7

Poids moléculaire: 32 kDa

ID gène: 79444

OMIM: 605737

UniProt: Q96CA5