OCRL anticorps (AA 150-199)
Aperçu rapide pour OCRL anticorps (AA 150-199) (ABIN1453701)
Antigène
Voir toutes OCRL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 150-199
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Fonction
- OCRL Antibody
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Specificité
- OCRL Polyclonal Antibody detects endogenous levels of OCRL protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from human OCRL. AA range:150-199
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))
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Autre désignation
- OCRL
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Sujet
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Synonyms: OCRL, INPP5F, OCRL1, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome protein
Background: This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
Gene Name: OCRL
Protein Name: Inositol polyphosphate 5-phosphatase OCRL-1
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Poids moléculaire
- 104 kDa
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ID gène
- 4952
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OMIM
- 300535
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UniProt
- Q01968
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Pathways
- Inositol Metabolic Process
Antigène
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