POT1 anticorps (AA 247-296)

N° du produit ABIN1453800

Cet anticorps anti-POT1 Polyclonal Lapin (ABIN1453800) détecte spécifiquement POT1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain et Singe.

Aperçu rapide pour POT1 anticorps (AA 247-296) (ABIN1453800)

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Reactivité: Humain, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-POT1 anticorps

Épitope: AA 247-296

Fonction: POT1 Antibody

Specificité: POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur POT1

Antigène: POT1 (Protection of Telomeres 1 (POT1))

Autre désignation: POT1

Sujet:

Synonyms: POT1, Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein

Background: protection of telomeres 1(POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008],

Gene Name: POT1

Protein Name: Protection of telomeres protein 1

Poids moléculaire: 71 kDa

ID gène: 25913

OMIM: 606478

UniProt: Q9NUX5

Pathways: Cycle Cellulaire, Telomere Maintenance