RUNX3 anticorps (AA 133-182)
Aperçu rapide pour RUNX3 anticorps (AA 133-182) (ABIN1453878)
Antigène
Voir toutes RUNX3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 133-182
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Fonction
- RUNX3 Antibody
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Specificité
- RUNX3 Polyclonal Antibody detects endogenous levels of RUNX3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from human RUNX3. AA range:133-182
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))
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Autre désignation
- RUNX3
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Sujet
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Synonyms: RUNX3; AML2; CBFA3; PEBP2A3; Runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEB
Background: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
Gene Name: RUNX3
Protein Name: Runt-related transcription factor 3
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Poids moléculaire
- 44 kDa
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ID gène
- 864
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OMIM
- 600210
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UniProt
- Q13761
Antigène
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