ALIX anticorps (AA 1-180)

N° du produit ABIN1512565

Cet anticorps Lapin Polyclonal détecte spécifiquement ALIX dans WB et IF. Il présente une réactivité envers Humain et a été mentionné dans 3+ publications.

Aperçu rapide pour ALIX anticorps (AA 1-180) (ABIN1512565)

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALIX est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-ALIX anticorps

Épitope: AA 1-180

Séquence: MATFISVQLK KTSEVDLAKP LVKFIQQTYP SGGEEQAQYC RAAEELSKLR RAAVGRPLDK HEGALETLLR YYDQICSIEP KFPFSENQIC LTFTWKDAFD KGSLFGGSVK LALASLGYEK SCVLFNCAAL ASQIAAEQNL DNDEGLKIAA KHYQFASGAF LHIKETVLSA LSREPTVDIS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human ALIX / PDCD6IP (NP_037506.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-ALIX (ABIN1512565)

Bei, Xu, Lv, Yu, Xu, Che, Das, Tigges, Toxavidis, Ghiran, Shah, Li, Zhang, Das, Xiao: "Exercise-induced circulating extracellular vesicles protect against cardiac ischemia-reperfusion injury." dans: Basic research in cardiology, Vol. 112, Issue 4, pp. 38, (2018) (PubMed).

Xu, Qin, An, Tang, Huang, Zheng: "MiR-145 detection in urinary extracellular vesicles increase diagnostic efficiency of prostate cancer based on hydrostatic filtration dialysis method." dans: The Prostate, Vol. 77, Issue 10, pp. 1167-1175, (2017) (PubMed).

Zhao, Wu, Duan, Ma, Shen, Wei, Cui, Zhang, Xie, Liu: "Quantitative proteomic analysis of exosome protein content changes induced by hepatitis B virus in Huh-7 cells using SILAC labeling and LC-MS/MS." dans: Journal of proteome research, Vol. 13, Issue 12, pp. 5391-402, (2015) (PubMed).

Détails sur ALIX

Antigène: ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

Autre désignation: PDCD6IP

Sujet: This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15.,PDCD6IP,AIP1,ALIX,DRIP4,HP95,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,PDCD6IP

Poids moléculaire: 30 kDa/96 kDa

ID gène: 10015

UniProt: Q8WUM4

Pathways: Signalisation p53, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation