IDO1 anticorps (AA 204-403)

N° du produit ABIN1513093

Cet anticorps Lapin Polyclonal détecte spécifiquement IDO1 dans WB, IHC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour IDO1 anticorps (AA 204-403) (ABIN1513093)

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-IDO1 anticorps

Épitope: AA 204-403

Séquence: ASCLEKALQV FHQIHDHVNP KAFFSVLRIY LSGWKGNPQL SDGLVYEGFW EDPKEFAGGS AGQSSVFQCF DVLLGIQQTA GGGHAAQFLQ DMRRYMPPAH RNFLCSLESN PSVREFVLSK GDAGLREAYD ACVKALVSLR SYHLQIVTKY ILIPASQQPK ENKTSEDPSK LEAKGTGGTD LMNFLKTVRS TTEKSLLKEG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 204-403 of human IDO1 (NP_002155.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IDO1

Antigène: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Autre désignation: IDO1

Sujet: This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.,IDO1,IDO,IDO-1,INDO,indoleamine 2,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,Immunology & Inflammation,Cardiovascular,IDO1

Poids moléculaire: 45 kDa

ID gène: 3620

UniProt: P14902

Pathways: Activated T Cell Proliferation