MEF2A anticorps (pSer408)

N° du produit ABIN1531188

Cet anticorps Lapin Polyclonal détecte spécifiquement MEF2A dans WB, IHC, IF et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MEF2A anticorps (pSer408) (ABIN1531188)

Antigène: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEF2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA

Détail du produit anti-MEF2A anticorps

Épitope: AA 374-423, pSer408

Fonction: MEF-2 (phospho Ser408) Antibody

Specificité: Phospho-MEF-2 (S408) Polyclonal Antibody detects endogenous levels of MEF-2 protein only when phosphorylated at S408.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human MEF2A around the phosphorylation site of Ser408. AA range:374-423

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MEF2A

Antigène: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Autre désignation: MEF2A

Sujet:

Synonyms: MEF2A, MEF2, Myocyte-specific enhancer factor 2A, Serum response factor-like protein 1

Background: The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010],

Gene Name: MEF2A

Protein Name: Myocyte-specific enhancer factor 2A

Poids moléculaire: 54 kDa

ID gène: 4205

OMIM: 600660

UniProt: Q02078

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades