EEF2K anticorps (pSer366)

N° du produit ABIN1531227

Cité dans 1 publication. Cet anticorps anti-EEF2K Polyclonal Lapin (ABIN1531227) détecte spécifiquement EEF2K dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour EEF2K anticorps (pSer366) (ABIN1531227)

Antigène: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EEF2K est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-EEF2K anticorps

Épitope: AA 331-380, pSer366

Fonction: eEF2K (phospho Ser366) Antibody

Specificité: Phospho-eEF2K (S366) Polyclonal Antibody detects endogenous levels of eEF2K protein only when phosphorylated at S366.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Pureté: > 95 %

Immunogène: The antiserum was produced against synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366. AA range:331-380

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Références pour anticorps anti-EEF2K (ABIN1531227)

Usui, Nijima, Sakatsume, Otani, Kameshima, Okada, Yamawaki: "Eukaryotic elongation factor2 kinase controls proliferation and migration of vascular smooth muscle cells." dans: Acta physiologica (Oxford, England), (2014) (PubMed).

Détails sur EEF2K

Antigène: EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

Autre désignation: eEF2K

Sujet:

Synonyms: EEF2K, Eukaryotic elongation factor 2 kinase, eEF-2 kinase, eEF-2K, Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase

Background: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008],

Gene Name: EEF2K

Protein Name: Eukaryotic elongation factor 2 kinase

Poids moléculaire: 82 kDa

ID gène: 29904

OMIM: 606968

UniProt: O00418

Pathways: AMPK Signaling