WNK1 anticorps (pThr58)
Aperçu rapide pour WNK1 anticorps (pThr58) (ABIN1531249)
Antigène
Voir toutes WNK1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 24-73, pThr58
-
Fonction
- WNK1 (phospho Thr60) Antibody
-
Specificité
- Phospho-WNK1 (T60) Polyclonal Antibody detects endogenous levels of WNK1 protein only when phosphorylated at T60.
-
Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Pureté
- > 95 %
-
Immunogène
- The antiserum was produced against synthesized peptide derived from human WNK1 around the phosphorylation site of Thr58. AA range:24-73
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store at -20°C/1 year
-
Date de péremption
- 12 months
-
-
- WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))
-
Autre désignation
- WNK1
-
Sujet
-
Synonyms: WNK1, HSN2, KDP, KIAA0344, PRKWNK1, Serine/threonine-protein kinase WNK1, Erythrocyte 65 kDa protein, p65, Kinase deficient protein, Protein kinase lysine-deficient 1, Protein kinase with no lysine 1, hWNK1
Background: This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.[provided by RefSeq, May 2010],
Gene Name: WNK1
Protein Name: Serine/threonine-protein kinase WNK1
-
Poids moléculaire
- 250 kDa
-
ID gène
- 65125
-
OMIM
- 145260
-
UniProt
- Q9H4A3
Antigène
-